Workflow of mRNA COMD process development 

TriVac

TriVac is a patented technology of antigen functional modification, which enhances antigen presentation and induction as well as promote specific acquired immune responses by modifying the structure of various antigens including mRNA,DNA encoded proteins or recombinant proteins. TriVac efficiently activates three specific lymphocytes of the acquired immune system such as B cells, CD4  T cells and CD8  T cells through three functional modifications of antigens achieving the great enhancement of the antigen-specific immune response.TriVac is owned by Duke University and Johns Hopkins University invented by He Youwen, Sun Hegang, Thomas August, Liu Jun and Wei Yadong . 

DNA template Manufacturing

Provide DNA template manufacturing and relative analysis.

GMP mRNA development and manufacturing

Provide a clear path to GMP mRNA manufacturing including process development, optimization,scale-up and GMP manufacturing：

Manufacture capability from mg to g meeting customized demands.

Tricision patented technology of mRNA manufacturing leading to shorten timelines,lower costs and higher quality.

The use of domestic GMP-level materials streamline the transition from discovery to phase I clinical trials in order to reduce the cost of large-scale manufacturing, material changes and material detections.

Quality control of mRNA