Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12.
Zhang, H., Y. Wang, Q. T. Wang, S. N. Sun, S. Y. Li, H. Shang and Y. W. He (2020). "Enhanced Human T Lymphocyte Antigen Priming by Cytokine-Matured Dendritic Cells Overexpressing Bcl-2 and IL-12." Front Cell Dev Biol 8: 205.
The data suggest that DC matured by the four-cytokine cocktail (TNF-α, IL-6, IL-1β, and PGE2) combined with exogenous Bcl-2 and IL-12p70 gene expression represents a promising approach for producing DC vaccines.
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